Anxiety Research

EQUITy: Enhancing the quality of psychological interventions delivered by telephone

The EQUITy programme is a £2.4 million research programme funded by the National Institute of Health Research’s Programme Grants for Applied Research funding stream. It aims to improve the way psychological therapies for depression and anxiety are delivered by telephone so that we can ensure that people receive the care that they need.

Depression and anxiety are common mental health problems that can cause substantial difficulties for people who experience them. The NHS has created an innovative psychological therapy service called Improving Access to Psychological Therapy (IAPT), to help people with these conditions. EQUITy is working closely with patients and professionals to ensure the work is acceptable to the people accessing IAPT services and those supporting patients.

If you would like to take part or would like further information about the programme you can email us at


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Ends:1st October 2023

Genetic Links to Anxiety & Depression

Exciting new opportunity to engage in anxiety/depression research

Depression and anxiety are common but complex disorders whose research needs very large sample sizes. The Genetic Links to Anxiety and Depression (GLAD) study launches this September and aims to recruit >40,000 individuals. Anyone age 16 years or older who has experienced anxiety or depression during their lives can join this recontactable database to facilitate future research. Participants will also join a national Mental Health BioResource and contribute to the largest ever single study of anxiety and depression.

How can I take part?

All enrollment takes place online at our website, An online animation explains the consent process with more detailed information in text format. Once you have provided consent and completed an online questionnaire you will be sent a saliva DNA sample kit to enable genetic studies.

We really hope you will join us in this important endeavour.


Ends 29/01/2028

Covid Anxiety Project (CAP)

While it is normal to be worried about COVID, people with COVID anxiety become so worried they cannot function properly. These individuals spend a lot of time worrying about their health, and thinking about COVID may make them feel unwell or keep them awake at night.

Imperial College London is leading a study that aims to find out how best to help people who experience these problems. If you or someone you know is experiencing these problems, we encourage you to go to take part in our research via our online survey: or call 020 7594 3253 to be contacted by a member of the research team.

Volunteers will first be asked 5 questions to assess the scale of their anxiety towards COVID. People with high scores will be asked to complete the full survey, which asks a range of questions about participants’ thoughts and feelings about COVID. The full survey will take around 20-30 minutes to complete.

Further information about the study can be found at:

Ends 1st Dec 2021

Mothers’ and fathers’ perceptions of their kids’ risky play: An online vignette study

The CAPE (Childhood, Attachment, Play and Emotions) Lab at University of Sussex is conducting research that investigates the potential relationship between parental anxiety, child anxiety and children’s experiences of risky and adventurous play.

We are currently inviting UK resident mums and dads with a child aged 2-7 (not yet in Year 3) to complete an online study about their child’s risky and adventurous play.

The study will involve reading different risky and adventurous play scenarios and then answering questions about each scenario. You will also be asked questions about your beliefs about children’s risky play, your child’s engagement in risky and adventurous play, and how you supervise their play. Additionally, you’ll be asked some questions about you and your child’s feelings of anxiety and low mood.

The survey should take 30-45mins to complete and you can choose to provide your e-mail address to receive a £5 Amazon voucher for your participation.

You can access the survey here to find out more information and take part:

If you have any questions about taking part, feel free to contact the lead researcher, Toni Brown (

Living with depression or anxiety?

Double-Blind, Placebo-Controlled, Multi-Center Study Investigating the Efficacy, Safety, and Tolerability of JNJ-61393215 as Adjunctive Treatment in Adults with Major Depressive Disorder with Anxious Distress with Suboptimal Response to Standard Antidepressants.

MAC understand that not all patients respond sufficiently well to current antidepressants and there is a need for more effective treatments for those with depression and anxiety. Therefore, MAC is currently conducting a clinical trial to evaluate an investigational drug for depression with anxious distress. Addressing anxiety symptoms in the context of depression may lead to improved outcomes for patients and more rapid relief of depression symptoms.

The purpose of this trial is to see if the investigational study drug is safe and effective for treating patients with Major Depressive Disorder (MDD) with anxious distress who have not had an adequate response to their current antidepressant medication. The study has a 1:1 ratio with placebo (dummy drug) and you will take the study medication for six weeks. You will stay on your current anti-depressant therapy throughout the trial.
This trial will run at our Barnsley, Liverpool, and Manchester sites.

Study Length: approximately 12 weeks.
No. of Visits: 7
Route of administration: Oral capsule.
Payment: £545.
Key inclusion criteria
• Male or female aged 18 – 64
• Diagnosis of depression with anxious distress
• Currently taking a stable dosage of eligible SSRI/SNRI
Key exclusion criteria
• A diagnosis of any major psychiatric condition including the following: delusions or hallucinations present along with depression, bipolar disorder, borderline personality disorder Schizophrenia, eating disorder, obsessive-compulsive disorder
• History of MS, optic neuritis or any demyelinating disease
This is not a complete list of qualifying criteria.

A full description of the study will be given before you decide to take part, both over the phone and during an appointment at a MAC clinic. This will include you receiving the full patient information sheet (PIS).Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with your treating physician.

Barnsley: +44 (0) 1226 356940 Liverpool: +44 (0) 151 4824700 Manchester: +44 (0) 161 2759966

Contact Alex Billington


Ends 2022

Does your child have Obsessive Compulsive Symptoms/Disorder (OCD)?

The University of Reading are conducting a study to see if supporting parents/carers to apply Cognitive Behavioural Therapy (CBT) techniques at home helps to reduce OCD symptoms in children.

This study is relevant to you if:

  • Your child is aged 5 to 12 years old
  • Your child has OCD or you think your child may have OCD

What will I be asked to do?

  • Complete short screening questions
  • Attend interviews to see if your child has OCD and some other common difficulties.
  • Fill out short weekly questionnaires for 3, 4 or 5 weeks.
  • Receive 6 to 8 treatment sessions with a therapist and complete activities at home with your child.
  • Attend follow-up interviews to see if your child’s symptoms have reduced.

What will my child be asked to do?

  • Your child can attend the interviews with you to help us to understand their experiences of OCD. Your child’s attendance at these interviews is optional.
  • Complete activities at home with you.

For more information visit:

Contact: Chloe Chessell

Ends 31st March 2022

List Your Anxiety Research

You can submit your anxiety research for listing on our website by filling out a submission form.

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